The Turkish Journal of Pediatrics 2003 , Vol 45 , Num 2
Acrocyanosis as a side effect of tricyclic antidepressants: A case report

Department of Child and Adolescent Psychiatry, Kocaeli University Faculty of Medicine, İzmit, Turkey

Department of Pediatrics, Kocaeli University Faculty of Medicine, İzmit, Turkey


Acrocyanosis is probably the most unusual side effect of tricyclic antidepressant drugs. In this paper, we report a 10-year-old boy with primary enuresis nocturna and attention deficit hyperactivity disorder who developed two episodes of acrocyanosis, the first of which was after imipramine treatment and the second after desipramine usage. We also review the possible pathogenesis of acrocyanosis. We suggest that physicians should be aware of this rare side effect of tricyclic antidepressants.

Keywords : acrocyanosis tricyclic antidepressants side effect
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