The Turkish Journal of Pediatrics 2008 , Vol 50 , Num 1
Weekly long-term intravenous immunoglobulin for refractory parvovirus B19 and Epstein-Barr virus-induced immune thrombocytopenic purpura
Pediatric Hematology Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey Tavil B, Ünal Ş, Aytaç-Elmas S, Yetgin S. Weekly long-term intravenous immunoglobulin for refractory parvovirus B19 and Epstein-Barr virusinduced immune thrombocytopenic purpura. Turk J Pediatr 2008; 50: 74-77.

In pediatric acute immune thrombocytopenic purpura (ITP) cases, it is usually possible to determine an underlying pathology; among them, viral infections are the leading causative agents. In this report, we describe two cases of acute ITP complicated secondary to parvovirus B19 or Epstein-Barr virus (EBV) infections who were unresponsive to initial therapeutic measures, but who responded to long-term intravenous immunoglobulin (IVIG) treatment, given weekly for five to eight weeks. Keywords : acute immune thrombocytopenic purpura, intracranial hemorrhage, parvovirus B19, Epstein-Barr virus, long-term IVIG treatment

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