The Turkish Journal of Pediatrics 2003 , Vol 45 , Num 4
Prenatal diagnosis of Cantrell's pentalogy: a case report

Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Turkey

Social Security Ankara Maternity Hospital, Ankara, Turkey

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey


A 23 year-old nulliparous woman was admitted to the obstetrics clinic in the 12th week of her pregnancy. Following the first trimester scanning, the fetus was diagnosed as having a large omphalocele and ectopia cordis. It was thought to be a thoracoabdominal wall defect and a possible case of Cantrells pentalogy. Amniocentesis was performed and at the 16th week, the pregnancy was terminated because of karyotype revealing trisomy 21 and the serious structural defects. Autopsy demonstrated an ectopia cordis without pericardium and an abdominal wall defect with an omphalocele. Fetus had no diaphragma or sternum, and pulmonary and extremity anomalies were also present. With these findings, this case is suggested to be a variant of Cantrells pentalogy.

Keywords : Cantrell's pentalogy trisomy 21 prenatal diagnosis
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