The Turkish Journal of Pediatrics 2008 , Vol 50 , Num 3
Unilateral juvenile (virginal) hypertrophy of the breast
1 Department of Pediatric Oncology, Dokuz Eylül University Institute of Oncology, Izmir, Turkey
2 Departments of Pathology, Dokuz Eylül University Institute of Oncology, Izmir, Turkey
3 Departments of General Surgery, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey,
4 Department of Pediatric Endocrinology, Spectrum Health, DeVos Children's Hospital, Grand Rapids, Michigan, USA
Güneş D, Mutafoğlu-Uysal K, Canda T, Saydam S, Cemeroğlu AP, Olgun N. Unilateral juvenile (virginal) hypertrophy of the breast. Turk J Pediatr 2008; 50: 278-281.

Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The etiology of JHB is uncertain. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. The definitive diagnosis is made by histopathologic examination. Treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in pediatric patients. Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment. Keywords : juvenile hypertrophy of breast, adolescent, management

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