The Turkish Journal of Pediatrics 2022 , Vol 64 , Num 6
Spontaneous remission of nephrotic syndrome associated with COVID-19 infection in an 8-year-old boy
Aylin Kayalı Akyol 1 ,Gamze Akça Dinç 2 ,Özlem Mustafaoğlu 3 ,Aysun Yahşi 3 ,Gülsüm İclal Bayhan 4 ,Sare Gülfem Özlü 5
1 Department of Pediatrics, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
2 Division of Pediatric Nephrology, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
3 Division of Pediatric Infectious Disease, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
4 Division of Pediatric Infectious Diseases, Ankara City Hospital, Yıldırım Beyazıt University Faculty of Medicine,
5 Division of Pediatric Nephrology, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
DOI : 10.24953/turkjped.2021.4559 Background. It is already known that viral infections, exclusively upper respiratory tract infections may trigger relapses of nephrotic syndrome. Recently, COVID-19 disease has also been reported to be related with relapse of nephrotic syndrome in a few pediatric cases

Case. Here we present an 8-year-old boy who had relapse of nephrotic syndrome due to COVID-19 infection. He was asymptomatic except for mild edema. He was managed supportively, no medication was started and went into spontaneous remission in 7 days.

Conclusions. Viral infections particularly upper respiratory tract infections may trigger relapse of nephrotic syndrome. COVID-19 has also been reported to be related with relapses of nephrotic syndrome in a few pediatric cases. Spontaneous remission in our patient indicates the importance of close monitoring of patients before starting long term treatment with steroids. Keywords : COVID-19, SARS-CoV-2, nephrotic syndrome, child

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