The Turkish Journal of Pediatrics
2022 , Vol 64 , Num 6
Spontaneous remission of nephrotic syndrome associated with COVID-19 infection in an 8-year-old boy
1 Department of Pediatrics, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye2 Division of Pediatric Nephrology, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
3 Division of Pediatric Infectious Disease, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye
4 Division of Pediatric Infectious Diseases, Ankara City Hospital, Yıldırım Beyazıt University Faculty of Medicine,
5 Division of Pediatric Nephrology, Ankara City Hospital, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye DOI : 10.24953/turkjped.2021.4559 Background. It is already known that viral infections, exclusively upper respiratory tract infections may trigger relapses of nephrotic syndrome. Recently, COVID-19 disease has also been reported to be related with relapse of nephrotic syndrome in a few pediatric cases
Case. Here we present an 8-year-old boy who had relapse of nephrotic syndrome due to COVID-19 infection. He was asymptomatic except for mild edema. He was managed supportively, no medication was started and went into spontaneous remission in 7 days.
Conclusions. Viral infections particularly upper respiratory tract infections may trigger relapse of nephrotic syndrome. COVID-19 has also been reported to be related with relapses of nephrotic syndrome in a few pediatric cases. Spontaneous remission in our patient indicates the importance of close monitoring of patients before starting long term treatment with steroids.
Keywords : COVID-19, SARS-CoV-2, nephrotic syndrome, child