The Turkish Journal of Pediatrics 2019 , Vol 61 , Num 1
More than Ophelia syndrome: Multiple paraneoplastic syndromes in pediatric Hodgkin lymphoma
Uğur Demirsoy 1 ,Burcu Alparslan 2 ,Mehmet Celal Şen 3 ,Yonca Anık 2 ,Gür Akansel 2 ,Gözde Görür 4 ,Bora Gürel 5 ,Görkem Aksu 6 ,Funda Çorapcıoğlu 1
1 Departments of Pediatric Oncology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
2 Departments of Radiology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
3 Departments of Pediatric Surgery, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
4 Departments of Nuclear Medicine, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
5 Departments of Pathology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
6 Departments of Radiation Oncology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
DOI : 10.24953/turkjped.2019.01.024 Demirsoy U, Alparslan B, Şen MC, Anık Y, Akansel G, Görür G, Gürel B, Aksu G, Çorapçıoğlu F. More than Ophelia syndrome: Multiple paraneoplastic syndromes in pediatric Hodgkin lymphoma. Turk J Pediatr 2019; 61: 139-141.

Paraneoplastic syndromes in Hodgkin lymphoma (HL) can be seen with different symptoms and organ findings within a significant time before definite diagnosis of the primary disease. Achalasia, Holmes-Adie pupil, and limbic encephalitis are rarely reported paraneoplastic components in pediatric HL. In this report, we present an 11-year-old girl who had all these three paraneoplastic components synchronously before HL was identified. Keywords : achalasia, Hodgkin lymphoma, Holmes-Adie pupil, limbic encephalitis, paraneoplastic syndrome

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