The Turkish Journal of Pediatrics
2013 , Vol 55 , Num 4
Posterior Reversible Encephalopathy Syndrome due to Pulse Methylprednisolone Therapy in a Child
Division of 1Pediatric Neurology, 2Pediatric Intensive Care Unit, and 3Pediatric Immunology, Department of Pediatrics,
Çukurova University Faculty of Medicine, Adana, Turkey. E-mail: fincecik@yahoo.com
Posterior reversible leukoencephalopathy syndrome (PRES) is a recently
described disorder with typical radiological findings of bilateral grey and white
matter abnormalities in the posterior regions of the cerebral hemispheres. It has
been described in children in association with some medications, renal disease,
autoimmune disease, transplantation, and sepsis. In this report, we discuss
an eight-year-old boy with PRES during pulse methylprednisolone therapy. In
conclusion, PRES is a neurological complication of pulse methylprednisolone
therapy, which responds favorably to prompt therapy withdrawal and blood
pressure control.
Keywords :
posterior reversible leukoencephalopathy syndrome, pulse methylprednisolone
therapy, children.