The Turkish Journal of Pediatrics
2012 , Vol 54 , Num 3
Rubella Vaccination during the Preconception Period or in Pregnancy and Perinatal and Fetal Outcomes
Department of Gynecology and Obstetrics, Ege University Faculty of Medicine, İzmir, Turkey
The rubella vaccine is contraindicated in pregnancy. Between July and
August 2009, the Turkish Republic Ministry of Health implemented a vaccine
program to eradicate rubella in women in the reproductive period. In this
program, many pregnant women were also vaccinated inadvertently. In this
study, 62 pregnant women applied to our clinic who were vaccinated either
during pregnancy or within one month before the last menstrual period.
Seventeen of them were followed until the end of the pregnancy by fetal
echocardiography and detailed ultrasonography. Rubella immunoglobulin (Ig)
M and IgG antibodies were studied in the cord blood obtained at birth. All
fetuses were examined by a pediatrician, an ophthalmologist and a pediatric
cardiologist. A hearing test was also performed on all neonates. No signs of
congenital rubella syndrome could be found.
Keywords :
rubella vaccination, preconception period, outcome.