The Turkish Journal of Pediatrics 2022 , Vol 64 , Num 5
Giant cell tumor arising from the anterior arc of the rib: an extremely rare site in an adolescent girl
Gül Özyüksel 1 ,Burak Ardıçlı 1-2 ,H. Nursun Özcan 3 ,Gökhan Gedikoğlu 4 ,Ali Varan 5 ,İbrahim Karnak 1-2
1 Departments of Pediatric Surgery, Hacettepe University Faculty of Medicine, Ankara
2 Department of Medical and Surgical Research, Hacettepe University Institute of Health Sciences, Ankara, Türkiye
3 Departments of Radiology, Hacettepe University Faculty of Medicine, Ankara
4 Departments of Pathology, Hacettepe University Faculty of Medicine, Ankara
5 Departments of Pediatric Oncology, Hacettepe University Faculty of Medicine, Ankara
DOI : 10.24953/turkjped.2021.4588 Background. Giant cell tumor is a rare and locally aggressive neoplasm of the long bones in children. Rib is the least frequently affected site, seen in less than 1% of all cases and most of them occur at the posterior arc.

Case. A 12-year-old girl presented with swelling and slight pain on the left inferior-anterior chest wall for two years. Physical examination revealed a giant, hard and fixed mass on the left chest wall. Hematological and biochemical test results were in normal limits but slight elevation of alkaline phosphatase level. Computed tomography of the chest showed a large expansive mass and lytic lesion with internal calcification arising from the anterior part of the 7th rib. En-bloc resection was performed including the 6th-8th ribs and a small part of the diaphragm. The pathological evaluation revealed giant cell tumor of bone.

Conclusions. Herein, we aim to emphasize that giant cell tumor should be considered in the differential diagnosis of chest wall tumors in childhood whereby en-bloc resection and close follow up would be paramount. Keywords : giant cell tumor, costa, chest wall tumor, child, treatment

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