The Turkish Journal of Pediatrics
2010 , Vol 52 , Num 3
Anti-GQ1b-Negative Miller Fisher Syndrome Presented with One-Sided Horizontal Gaze Palsy
1Division of Pediatric Neurology, Department of Pediatrics, and 2Department of Neurology, Dokuz Eylül University
Faculty of Medicine, İzmir, Turkeym
Miller Fisher syndrome classically presents with ophthalmoplegia, ataxia and
areflexia. The syndrome may present rarely with atypical clinical features.
Whether the central or peripheral nervous system is primarily involved remains
controversial. Miller Fisher syndrome usually follows an infection, the most
likely being Campylobacter jejuni. Mycoplasma pneumoniae has been reported
rarely as the antecedent infectious agent in some patients.
Herein, we report a 13-year-old girl with positive mycoplasma immunoglobulin (Ig)M and IgG serology who presented with one-sided horizontal gaze palsy, ataxia, areflexia, and bulbar palsy. Her cranial magnetic resonance imaging was normal and blood serum was negative for anti-GQ1b IgG antibodies.og
Keywords : Miller Fisher syndrome, horizontal gaze palsy, mycoplasma, bulbar palsy.