The Turkish Journal of Pediatrics 2008 , Vol 50 , Num 4
Is Escherichia coli O157:H7 a common pathogen in children with bloody diarrhea in Shiraz, Iran?
Prof. Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Alborzi A, Aelami MH, Astaneh B, Pourabbas B, Farshad S, Kalani M, Nasiri J, Rashidi M. Is Escherichia coli O157:H7 a common pathogen in children with bloody diarrhea in Shiraz, Iran? Turk J Pediatr 2008; 50: 349-353.

Escherichia coli (E. coli) O157:H7 is a common cause of bloody diarrhea in developed countries. The aim of this study was to determine whether E. coli O157:H7 is a possible pathogen of bloody diarrhea in southern Iran. Out of 719 children with diarrhea, 243 (34%) patients with positive occult blood took part in our study. The polyclonal antibody test and polymerase chain reaction (PCR) were used to identify E. coli O157:H7. Stool cultures showed enteropathogens in 107 patients (44%). Shigella (34.3%) was followed by E. coli (8.6%), campylobacter (2%) and salmonella (0.4%). None of the E. coli species was of O157:H7 serotype. Antibiotic sensitivity of shigella species was 100% to ceftriaxone, ciprofloxacin and ceftazidime, 94% to nalidixic acid and 13% to co-trimoxazole. The results of the study showed that E. coli O157: H7 is not a cause of bloody diarrhea in our area. Keywords : Escherichia coli O157:H7, bloody diarrhea, children, Iran

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