The Turkish Journal of Pediatrics 2012 , Vol 54 , Num 1
Successful Treatment of Multidrug-Resistant Escherichia coli Bacteremia with Tigecycline in an Acute Myeloid Leukemia Child
Divisions of 1Pediatric Infectious Diseases and 2Pediatric Hematology/Oncology, Department of Pediatrics and 3Microbiology Laboratory, Ankara University Faculty of Medicine, Ankara, Turkey Özdemir H, Çiftçi E, Karbuz A, Oktay G, Aysev D, Yavuz G, İnce E. Successful treatment of multidrug-resistant Escherichia coli bacteremia with tigecycline in an acute myeloid leukemia child. Turk J Pediatr 2012; 54: 59-60.

The multidrug-resistant bacterial infections cause high mortality in immunocompromised patients because of the limited antibacterial choices. Tigecycline, first member of the glycylcyclines, has in vitro activity against a wide variety of organisms, including multidrug-resistant pathogens; however, it has not yet been approved for use in children. Herein, we report a nine-year-old girl with acute myeloid leukemia who was treated successfully with tigecycline due to multidrug-resistant Escherichia coli bacteremia. Keywords : child, Escherichia coli, leukemia, tigecycline.

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