Warning: fopen(uploads/logs/2020_09_29.txt): failed to open stream: Permission denied in /home/virtual/turkishjournalpediatrics.org/include/class_system.php on line 836

Warning: fclose() expects parameter 1 to be resource, boolean given in /home/virtual/turkishjournalpediatrics.org/include/class_system.php on line 842
The Turkish Journal of Pediatrics
The Turkish Journal of Pediatrics 2020 , Vol 62 , Num 4
A rare cause of secondary hemophagocytic lymphohistiocytosis: systemic loxoscelism
Tuğba Erat 1 ,Aysun Yahşi 1 ,Cem Çanakçı 2 ,Aybike Korkmaz 2 ,Ceyda Karahan 2 ,Talia İleri 3 ,Savaş Serel 4 ,Huban Atilla 5 ,Nihal Kundakçı 6 ,Halil Özdemir 1 ,Erdal İnce 1 ,Ergin Çiftçi 1
1 Divisions of Pediatric Infectious Diseases,Ankara University Faculty of Medicine, Ankara, Turkey
2 Department of Pediatrcis, Ankara University Faculty of Medicine, Ankara, Turkey
3 Divisions of Pediatric Hematology and Oncology, Ankara University Faculty of Medicine, Ankara, Turkey
4 Departments of Plastic Reconstructive and Aesthetic Surgery, Ankara University Faculty of Medicine, Ankara, Turkey
5 Departments of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey
6 Departments of Dermatology, Ankara University Faculty of Medicine, Ankara, Turkey
DOI : 10.24953/turkjped.2020.04.014 Background. Loxoscelism is caused by the bite of a specific spider type called the Loxosceles genus. In Turkey, most cases are seen after L. rufescens bites. Clinical manifestation of the bites ranges from local cutaneous reaction to severe ulcerative necrosis. Systemic loxoscelism may also occur.

Case. Herein, we report a previously healthy five-year-old male patient who developed a secondary hemophagocytic lymphohistiocytosis after a presumed brown spider bite. He was treated with dexamethasone. Within the following 14 days, hemophagocytic syndrome resolved. Local hyperbaric oxygen therapy was applied to the necrotic areas.

Conclusion. Secondary hemophagocytic lymphohistiocytosis may develop after systemic loxoscelism. In the presence of persistent fever, hepatosplenomegaly and laboratory findings this clinical entity should be kept in mind. Keywords : hemophagocytic lymphohistiocytosis, necrotic arachnidism, systemic loxoscelism, violin spiders

Copyright © 2016 turkishjournalpediatrics.org